The results of gammaCore therapy vary from person to person and sadly will not work for everyone. One study showed that 39% of menstrual migraine sufferers benefited from using gammaCore as a preventive therapy. These patients reported; a reduction in the number of menstrual migraine days or menstrual related migraine symptoms, the use of less pain-relief medications, having reduced intensity of headaches and having a reduced disability associated with migraine.

In other studies the acute use of gammaCore at migraine onset provided relief for more than 50% of attacks reported, with almost half of the patients reporting little to no migraine pain within 2 hours after first use.

The most commonly reported side effects present during the act of stimulating the vagus nerve with gammaCore and resolve immediately after the stimulation is complete. These include but are not limited to:

  • Application site discomfort, irritation and redness
  • Local pain, face/head/neck area (including toothache)
  • Muscle twitching and/or contractions
  • Headache
  • Dizziness
  • Tingling, pricking, or a feeling of “pins and needles” on the skin where the device is applied.

No. If you are experiencing any pain, muscle soreness or discomfort then you may be using the device incorrectly.

Yes, you can only use gammaCore on your neck as shown in the training video and in the Instructions For Use booklet. gammaCore will not work if used on another site location.

gammaCore is indicated for the treatment and/ or prevention of primary headache (migraine, cluster headache, and hemicrania continua) and medication overuse headache in adults. Authorisation to use gammaCore must be approved by a healthcare professional. To complete a gammaCore order, please complete a health questionnaire which will be reviewed by a suitably qualified healthcare professional.

gammaCore cannot be used by people who:

  • Have an active implantable medical device, such as a pacemaker, hearing aid implant, or any implanted electronic device
  • Have a metallic device, such as a stent, bone plate, or bone screw, implanted at or near the neck

Safety and efficacy of gammaCore have not been evaluated in the following patients and therefore use cannot be recommended:

  • Adolescents and paediatrics
  • Patients diagnosed with narrowing of the arteries (carotid atherosclerosis)
  • Patients who have had surgery to cut the vagus nerve in the neck (cervical vagotomy)
  • Pregnant women
  • Patients with clinically significant hypertension, hypotension, bradycardia, or tachycardia

Yes, gammaCore is safe to use with any other prescribed or over the counter medication.

No. You are required to complete the assessment questionnaire before your first supply of gammaCore and then after a further 24 months. If there are any changes in your medical status please notify electroCore at customerserviceuk@electrocore.com so that your authorisation can be reviewed. You are otherwise required to confirm there have been no changes to your medical status prior to any purchase and you will have the opportunity to review your previously submitted responses.

No. gammaCore Sapphire devices are single patient use only and therefore once purchased become the property of the purchaser. The internal lithium battery life of the device is 3 years from first use and so subsequent courses of therapy are purchased and loaded onto the device by electronic transfer. Unless faulty (indicated by an error code) you are not required to return the device to us. Should you choose to stop using gammaCore please dispose of the device with other battery-operated electrical devices using your nearest recycling/battery collection point.

Contact electroCore UK Customer Service at customerserviceuk@electrocore.com if you have questions about the appropriate disposal of this device.

Yes, it is safe to travel with gammaCore. gammaCore contains a lithium battery, we recommend storing gammaCore in your carry-on luggage to assure it is not exposed to extreme temperature changes.

Yes. For more information please contact customerserviceuk@electrocore.com

Starter kits contain all the equipment you need to first start using gammaCore therapy. Refill kits should only be purchased following your initial Starter kit order. Once you have a device, this is yours and you only need to buy refill kits (courses of therapy) thereafter. Both the starter kit and refill kit come with sufficient gel to be used when delivering a stimulation.


Therapy is loaded onto a device using the refill cards. The system utilises similar technology as contactless card payment, where the refill cards are presented on the face of the device and held in place until therapy is received by the device.

No, the online questionnaire is currently only available in the UK.

If you live outside the UK please contact us at customerserviceeu@electrocore.com and we will be able to advise on gammaCore availability in your country.